FIG. 3.

Design of the HBV drug resistance research strip. Conj. cont., conjugate control; Amp. cont, amplification control. The strip contains a total of 19 probe lines; n probes equal the total amount of probes on each line, for a total of 38 probes. Interpretation of HBpol or HBsAg, amino acid for the polymerase or HBsAg ORF applied on this probe line, respectively. Several probes that were designed for different nucleotide polymorphisms (Polym.) but in which an amino acid change was not introduced were pooled and applied on one line.