TABLE 1.

Clonal analysis of follow-up samples

Patient and day	No. of clones with the following mutationsa:
	Total	L/M/V	L/M/I	L/V/V	M/M/V	M/V/V
Patient A
1	9	9	0	0	0	0
360	8	4	4	0	0	0
420	9	3	6	0	0	0
510	18	18	0	0	0	0
570	55	23	32	0	0	0
630	46	2	1	1	2	40
750	13	0	0	0	0	13
Total	158	59	43	1	2	53
Patient C
1	5	5	0	0	0	0
148	6	6	0	0	0	0
325	11	1	0	0	10	0
407	9	0	0	0	9	0
450	12	1	0	0	11	0
519	23	0	0	0	3	20
542	6	0	0	0	0	6
Total	72	13	0	0	33	26

^a 528/552/555.