Table 6.

Prospective study. Serum levels of routine biomarkers in COVID-19 cases without vitamin D treatment (C), COVID-19 cases in day 7 (D7), and in day 14 (D14) of vitamin D treatment.

	COVID-19 Cases (1–3 Days before Vitamin D Treatment) (C) (n = 209)	COVID-19 Cases (Day 7 of Vit D) (D7) (n = 99)	COVID-19 Cases (Day 14 of Vit D) (D14) (n = 86)	p Value for MCT
ALT (IU/L) Mean ± SD	29.08 ± 21.42	49.23 ± 44.76	53.22 ± 62.64	C vs. D7 or D14 p < 0.001; p > 0.05 for other groups
AST (IU/L) Mean ± SD	31.44 ± 23.41	35.61 ± 26.62	31.68 ± 29.86	p > 0.05 for all groups
CRP (mg/L) Mean ± SD	50.68 ± 66.41	28.13 ± 49.08	10.96 ± 27.27	C vs. D7 or D14 p < 0.001; D7 vs. D14 p < 0.001; p > 0.05 for other groups
Creatinine (mg/dL) Mean ± SD	1.03 ± 0.65	1.08 ± 1.02	0.87 ± 0.27	p > 0.05 for all groups
Sodium (mmol/L) Mean ± SD	137.08 ± 8.51	139.28 ± 3.69	139.63 ± 3.24	C vs. D7 or D14 p < 0.001; p > 0.05 for other groups
Urea (mg/dL) Mean ± SD	35.46 ± 22.64	40.77 ± 28.98	32.22 ± 16.44	p > 0.05 for all groups
Ferritin (ng/mL) Mean ± SD	408.15 ± 474.26	421.19 ± 498.75	252.52 ± 299.45	p > 0.05 for all groups
Hemoglobi Mean ± SD	12.43 ± 1.89	12.27 ± 1.80	12.69 ± 1.75	p > 0.05 for all groups
Lymphocyte (×103/µL) Mean ± SD	1.56 ± 0.82	1.60 ± 0.86	1.84 ± 0.65	C vs. D14 p < 0.001; D7 vs. D14 p < 0.05; p > 0.05 for other groups
Platelet (×103/µL) Mean ± SD	210.80 ± 81.10	296.25 ± 124.71	296.67 ± 91.07	C vs. D7 or D14 p < 0.001; p > 0.05 for other groups
Leukocyte (×103/µL) Mean ± SD	7.51 ± 7.55	8.31 ± 6.63	7.60 ± 3.02	C vs. D14 p < 0.01; p > 0.05 for other groups
D-dimer (mg/L) Mean ± SD	0.99 ± 1.21	1.08 ± 1.22	0.76 ± 0.83	p > 0.05 for all groups
Fibrinogen (mg/dL) Mean ± SD	469.60 ± 172.43	449.55 ± 148.01	375.42 ± 116.03	C vs. D14 p < 0.001; D7 vs. D14 p < 0.001; p > 0.05 for other groups

Bold letters indicating the group names or the significant data.