Core genome SNP based minimum spanning tree of stx1 positive S. flexneri strains isolated from four countries and their related travel history. These strains were isolated from patients in Canada (blue outer circles), U.S. (black outer circles), France (purple outer circles), and Haiti (red outer circles). The travel history is depicted by the filled colors of the circles with green (Dominican Republic), yellow (Haiti), light brown (French Guiana), and purple (Turks and Caicos Islands). Country specific Clusters I and II are shaded in light blue. Numbers on lines indicate core genome SNP differences between adjacent strains.