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. 2021 Nov 17;14(22):6945. doi: 10.3390/ma14226945

Figure 2.

Figure 2

mRNA level of osteogenic and inflammatory factors in peri-implant bone tissues. Panels (A,B): osteogenic factors; panel (C): WNT pathways; panel (D): inflammatory factors. Data represent the mean ± SEM of the evaluations carried out on bone samples obtained at T14. For each animal, the mRNA amounts detected at this time were normalized with respect to the values found in the corresponding bone at T0. Student’s t Test: BMP-4 * p = 0.017. BMP-4, bone morphogenetic protein-4; BMP-7, bone morphogenetic protein-7; TGF-β2, transforming growth factor-β2; RUNX2, RUNX family transcription factor 2; OCN, osteocalcin; ALP, alkaline phosphatase; COLL1A1, collagen 1A1; WNT, wingless-related MMTV integration site; IL-1β, interleukin-1β; IL-6, interleukin-6; IL-8, interleukin-8; TNF-α, tumor necrosis factor-α; IL-10, interleukin-10.