Table 1.
Effect of blackcurrant on plasma parameters in type 2 diabetes mellitus mice.
Parameters | Cont. | T2DM | Vil.G | Bla.C | ||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Cardiac risk ratio 1 (TC/HDL-C) |
1.217 | ± | 0.019 | 1.663 | ± | 0.086 ** | 1.298 | ± | 0.017 ## | 1.347 | ± | 0.080 ## |
Cardiac risk ratio 2 (LDL-C/HDL-C) |
1.600 | ± | 0.054 | 2.504 | ± | 0.246 ** | 1.651 | ± | 0.095 ## | 1.398 | ± | 0.097 ## |
Atherogenic coefficient (TC-HDL)/HDL-C |
0.217 | ± | 0.028 | 0.463 | ± | 0.096 *** | 0.298 | ± | 0.024 ### | 0.292 | ± | 0.026 ## |
Atherogenic marker (TG/HDL-C ratio) |
0.885 | ± | 0.095 | 1.285 | ± | 0.182 *** | 1.138 | ± | 0.120 # | 1.038 | ± | 0.238 # |
Atherogenic index log (TG/HDL-C) |
0.330 | ± | 0.046 | 0.475 | ± | 0.064 ** | 0.459 | ± | 0.040 # | 0.343 | ± | 0.038 ## |
Cont, control, db/m mice; T2DM, db/db mice, type 2 diabetes mellitus mice; Vil.G, db/db + vildagliptin 50 mg/kg/day, positive control, dipeptidyl peptidase-4 (DPP-4) inhibitor; Bla.C, db/db + blackcurrant 200 mg/kg/day; TC, total cholesterol; TG, triglyceride; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol. Data are shown as mean ± S.E. (n = 8 per group). ** p < 0.01, *** p < 0.001 vs. Cont.; # p < 0.05, ## p < 0.01, ### p < 0.001 vs. T2DM.