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. 2021 Nov 20;26(22):7022. doi: 10.3390/molecules26227022

Table 1.

Summary of different eutectic systems reported in the literature and their aim.

THEDES Aim Reference
Choline Chloride:Acetylsalicylic Acid
Choline Chloride:Phenylacetic Acid
Menthol:Benzoic Acid
Menthol:Acetylsalicylic Acid
Menthol:Phenylacetic Acid
Preparation of THEDES to study their bioavailability [24,25]
Menthol:Ibuprofen Incorporation of THEDES with NSAID in a polymeric matrix [26]
Choline Chloride:Mandelic Acid THEDES preparation and encapsulation in fiber membranes [27]
Choline Chloride:Ascorbic Acid Preparation of NADES and enhancement of dexamethasone solubility [28]
Citric Acid:Ethambutol:H2O Preparation of THEDES with API for TB [29]
Citric Acid:L-Arginine:H2O Encapsulation of THEDES in a lipidic carrier [30]
Menthol:Lauric Acid
Menthol:Myristic Acid
Menthol:Stearic Acid
Development of THEDES with terpenes and fatty acids with antimicrobial and wound healing properties [31]
Lauric Acid:Myristic Acid Preparation of eutectic blends and loading onto gauzes [32]
Capric Acid:Lauric acid
Capric Acid:Stearic Acid
Capric Acid:Myristic Acid
Preparation of different DES with fatty acids with antimicrobial activity and biofilm detachment [33]
Limonene:ibuprofen
Perillyl alcohol:ibuprofen
Menthol: ibuprofen
Thymol:ibuprofen
Preparation of THEDES with terpenes + NSAIDS and evaluation of their activity against CRC cells [34,35,36]