Table 2.
Predicted biological activities of steroid phosphate esters.
| No. | Lipid Metabolism Regulators, (Pa) * | Reported Activity | Ref. |
|---|---|---|---|
| 21 | Wound healing agent (0.975) Hepatoprotectant (0.961) Analeptic (0.952) Antihypercholesterolemic (0.926) Cholesterol synthesis inhibitor (0.799) |
Activity not studied | |
| 22 | Wound healing agent (0.947) Analeptic (0.941) Hepatoprotectant (0.932) Anticarcinogenic (0.915) Antihypercholesterolemic (0.912) Cholesterol synthesis inhibitor (0.778) |
Activity not studied | |
| 23 | Antihypercholesterolemic (0.900) Hepatoprotectant (0.853) Wound healing agent (0.844) Antineoplastic (0.816) Antiinflammatory (0.782) Cholesterol synthesis inhibitor (0.778) Atherosclerosis treatment (0.675) |
Activity not studied | |
| 24 | Neuroprotector (0.987) Anesthetic general (0.959) Respiratory analeptic (0.944) Antihypercholesterolemic (0.909) |
Substrate for phosphatases | [112] |
| 25 | Anesthetic general (0.991) Respiratory analeptic (0.990) Neuroprotector (0.976) Antiinflammatory (0.906) Antihypercholesterolemic (0.900) |
Increases blood sugar levels | [113] |
| 26 | Respiratory analeptic (0.979) Anesthetic general (0.973) Neuroprotector (0.972) Antihypercholesterolemic (0.971) Wound healing agent (0.913) Antineoplastic (0.826) Cholesterol synthesis inhibitor (0.801) |
Stabilizes blood pressure | [114] |
| 27 | Respiratory analeptic (0.995) Anesthetic general (0.948) Antihypercholesterolemic (0.945) Neuroprotector (0.932) Hemostatic (0.910) Wound healing agent (0.897) Cholesterol synthesis inhibitor (0.867) Acute neurologic disorders treatment (0.827) |
Reduces cholesterol levels | [116] |
| 28 | Antihypercholesterolemic (0.967) Wound healing agent (0.921) Neuroprotector (0.909) Cholesterol synthesis inhibitor (0.872) |
Reduces cholesterol levels | [116] |
| 29 | Antihypercholesterolemic (0.996) Cholesterol absorption inhibitor (0.976) Cholesterol synthesis inhibitor (0.952) Lipid metabolism regulator (0.952) Lipoprotein disorders treatment (0.893) |
Cholesterol biosynthesis inhibitor | [117] |
| 30 | Antihypercholesterolemic (0.999) Antihyperlipoproteinemic (0.986) Hypolipemic (0.974) Cholesterol absorption inhibitor (0.957) Lipid metabolism regulator (0.954) Cholesterol synthesis inhibitor (0.916) Lipoprotein disorders treatment (0.782) Acute neurologic disorders treatment (0.751) Atherosclerosis treatment (0.729) |
Cholesterol biosynthesis inhibitor | [117] |
| 31 | Neuroprotector (0.982) Anesthetic general (0.931) Antihypercholesterolemic (0.909) Acute neurologic disorders treatment (0.831) Prostate disorders treatment (0.640) |
Remedy for the treatment of prostate cancer | [118] |
* Only activities with Pa > 0.5 are shown.