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. 2021 Nov 22;19(11):650. doi: 10.3390/md19110650

Table 4.

Predicted biological activities of α,β-epoxy steroids.

No. Discovered Activity, (Pa) * Reported Activity Ref.
41 Apoptosis agonist (0.950)
Antihypercholesterolemic (0.931)
Antineoplastic (0.886)
Antieczematic (0.842)
Atherosclerosis treatment (0.712)
Cytotoxic [160]
42 Apoptosis agonist (0.950)
Antihypercholesterolemic (0.931)
Antineoplastic (0.886)
Antieczematic (0.842)
Atherosclerosis treatment (0.712)
Cytotoxic [160]
43 Apoptosis agonist (0.954)
Antineoplastic (0.914)
Antihypercholesterolemic (0.906)
Atherosclerosis treatment (0.741)
Activity not studied
44 Antihypercholesterolemic (0.934)
Apoptosis agonist (0.929)
Hypolipemic (0.864)
Antineoplastic (0.861)
Activity not studied
45 Hepatoprotectant (0.994)
Respiratory analeptic (0.990)
Antihypercholesterolemic (0.897)
Activity not studied
46 Antihypercholesterolemic (0.900)
Neuroprotector (0.749)
Cholesterol synthesis inhibitor (0.636)
Activity not studied
47 Antihypercholesterolemic (0.901)
Lipid metabolism regulator (0.833)
Prostate disorders treatment (0.714)
Anticancer [165]
48 Antihypercholesterolemic (0.924)
Lipid metabolism regulator (0.820)
Neuroprotector (0.728)
Anticancer [165]

* Only activities with Pa > 0.5 are shown.