Table 7.
Predicted biological activities of CBS steroids.
| No. | Discovered Activity, (Pa) * | Reported Activity | Ref. |
|---|---|---|---|
| 67 | Antihypercholesterolemic (0.902) Hypolipemic (0.721) Cholesterol synthesis inhibitor (0.534) |
Activity not studied | |
| 68 | Antihypercholesterolemic (0.932) Hypolipemic (0.695) Cholesterol synthesis inhibitor (0.588) |
Activity not studied | |
| 69 | Antineoplastic (0.915) Antihypercholesterolemic (0.900) Hypolipemic (0.897) Apoptosis agonist (0.892) Antineoplastic (liver cancer) (0.822) Chemopreventive (0.776) Atherosclerosis treatment (0.690) Cytoprotectant (0.611) Prostate cancer treatment (0.557) Antimetastatic (0.528) |
Cytotoxic | [206] |
| 70 | Antihypercholesterolemic (0.953) Hypolipemic (0.758) Lipid metabolism regulator (0.674) Atherosclerosis treatment (0.513) |
Antifungal | [207] |
| 71 | Antihypercholesterolemic (0.939) Hypolipemic (0.746) Lipid metabolism regulator (0.599) |
No activity detected | [207] |
| 72 | Antihypercholesterolemic (0.923) Hypolipemic (0.732) Atherosclerosis treatment (0.643) Cholesterol synthesis inhibitor (0.640) |
Activity not studied | |
| 73 | Hypolipemic (0.900) Atherosclerosis treatment (0.689) Cholesterol synthesis inhibitor (0.671) Antihypercholesterolemic (0.662) Lipid metabolism regulator (0.529) |
Activity not studied | |
| 74 | Antihypercholesterolemic (0.964) Hypolipemic (0.849) Antineoplastic (0.849) Antihyperlipoproteinemic (0.801) Cholesterol synthesis inhibitor (0.671) Atherosclerosis treatment (0.610) Prostate cancer treatment (0.601) |
Cytotoxic Anticancer |
[211,212,213,214] |
| 75 | Antihypercholesterolemic (0.923) Hypolipemic (0.732) Atherosclerosis treatment (0.643) Cholesterol synthesis inhibitor (0.640) |
Activity not studied | |
| 76 | Antihypercholesterolemic (0.935) Hypolipemic (0.731) Antihyperlipoproteinemic (0.689) Cholesterol synthesis inhibitor (0.600) |
Activity not studied | |
| 77 | Antihypercholesterolemic (0.908) Hypolipemic (0.726) Cholesterol synthesis inhibitor (0.589) Antihyperlipoproteinemic (0.587) |
Activity not studied | |
| 78 | Antihypercholesterolemic (0.969) Hypolipemic (0.810) Lipid metabolism regulator (0.716) Cholesterol synthesis inhibitor (0.707) Atherosclerosis treatment (0.586) |
Activity not studied |
* Only activities with Pa > 0.5 are shown.