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. 2021 Nov 10;21(22):7477. doi: 10.3390/s21227477

Table 3.

Adipose stem cells in scaffolds.

Biomaterial Effects Bioprinting Method * References
Alginate Increased BGLAP, COL1A1, SPP1 expression, round morphology, stiffness may encourage osteoblast differentiation, stemness preservation, low viability Inkjet [91,93,94]
Collagen Osteogenic genes are upregulated with inhibition of TNF-α, enhanced in vivo bone regeneration, multipolar or bipolar morphology - [98,99,100]
Gelatin Good cell proliferation and adhesion, ossification in vivo, enhance osteogenesis, early upregulation of OPN and RUNX2 - [101,102,103,104]
Hyaluronic Acid Can cause osteogenic, chondrogenic, or adipogenic differentiation, mineralized matrix formation and calcium deposition, long term cell preservation - [105,106,107]
Alginate/Collagen High viability and cell proliferation Custom [108]
Collagen/Hyaluronic Acid Strong cell proliferation, associated with chondrogenesis, greater hyaluronic concentration inhibits chondrogenesis - [109,110]

* If applicable.