Figure 2.

Similarity heat map for the evolution of Ca²⁺ signaling relative proteins, containing channels, pumps, antiporters, and sensors in different plant and algal species. Candidate protein sequences were selected by BLASTP searches which satisfied E value < 10⁻¹⁰ and query coverage > 50% [7]; colored squares indicate a protein sequence similarity from 20% (blue) to 100% (purple). White squares indicate proteins that satisfied neither of the selection criteria. GLRs, glutamate receptor-like channels; CNGCs, cyclic nucleotide gated channels; MSLs, mechanosensitive-like channels; MCAs, ‘mid1-complementing activity’ channels; TPC1, two-pore channel 1; OSCA1s, hyperosmolality-induced Ca²⁺ channel 1; ECAs, endoplasmic reticulum-type Ca²⁺-ATPases; ACAs, auto-inhibited Ca²⁺-ATPases; CaMs, calmodulin; CMLs, calmodulin-like protein; CBLs, calcineurin B-like protein; CIPKs, CBL-interacting protein kinases; CDPKs, Ca²⁺-dependent protein kinases.