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. 2021 Nov 10;11(11):3022. doi: 10.3390/nano11113022

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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(A) Schematic diagram for the synthesis of Cy5.5 or ^99mTc conjugated silica nanoparticles; (B) biodistribution of Cy5.5-conjugated silica nanoparticles in (a) liver (b) lung (c) spleen (d) testis (e) kidney and (f) heart, 2 h post-oral administration; (C) scintigraphic images of ^99mTc radiolabeled silica NPs after oral administration (SG—salivary glands, RAA—radiotracer administration aria, H—heart, S—spleen, L—liver, B—bladder, Bk—background). Reprinted with permission from [49], with permission from Elsevier, 2015.