Figure 7.

Model for the roles of cPLA2 and AA metabolism in SGIV infection. SGIV infection resulted in alteration of GPs homeostasis in vitro. Inhibition of cPLA2, COX, and 5-LOX significantly decreased SGIV replication. Inhibitors were shown in green. The key enzyme involved in GPs and AA metabolism were shown in blue. The lipid metabolites, which increased during SGIV infection, were shown in red. The lipid metabolites, which were not significantly changed in SGIV-infected cells, were shown in gray.