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. 2021 Nov 2;13(11):1839. doi: 10.3390/pharmaceutics13111839

Table 2.

Rat pharmacokinetic study of telocinobufagin.

Parameters (n = 3) I.V., 1 mg/kg P.O., 2 mg/kg
Tmax (h) NA 0.333 ± 0.144
Cmax (μg/h) NA 0.537 ± 0.227
T1/2 (h) 0.225 ± 0.02 0.51 ± 0.407
AUC (μg∙h/mL) 0.604 ± 0.159 0.488 ± 0.204
CL (L/h/kg) 1.73 ± 0.432 not applicable (NA)
Vss (L/kg) 0.275 ± 0.169 NA
Ft (%) NA 33.2