Figure 7.

Post-treatment ultrastructural SEM analysis of the apical surface topography of the nasal MucilAir™ in vitro models. Cultures were treated with 10-fold diluted mometasone nasal spray (A,A’), 10-fold diluted placebo nasal spray (B,B’), or culture medium (C,C’) for 14 consecutive days. Intact cultures were not treated (D,D’). Ciliated cells (arrows) and non-ciliated cells (asterisks) with apparent cell boundaries are observed in all cultures, regardless of the treatment. Arrowheads indicate artefacts. The red framed areas in images (A–D) are magnified in (A’–D’). Scale bars, 50 µm (A–D) and 25 µm (A’–D’).