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. 2021 Oct 20;13(11):1750. doi: 10.3390/pharmaceutics13111750

Figure 8.

Figure 8

Post-treatment ultrastructural TEM analysis of the nasal MucilAir™ in vitro models. Cultures were treated with 10-fold diluted mometasone nasal spray (A–C), 10-fold diluted placebo nasal spray (D–F), or culture medium (G–I) for 14 consecutive days. Intact cultures were not treated (J–L). Ciliated and non-ciliated cells are connected with junctional complexes (arrowheads in B,E,H,K) in all MucilAir™ cultures (treated and untreated). Well-formed tight junctions are seen in higher magnifications (arrows in C,F,I,L). Scale bars, 6 µm (D), 4 µm (J), 2 µm (A,G), 1 µm (B,E,H,K), 600 nm (F), and 400 nm (C,I,L).