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. 2021 Nov 17;9(11):1347. doi: 10.3390/vaccines9111347

Figure 2.

Figure 2

Physical properties of CoV-RBD121-NP. (A) Transmission electron microscopy of TMV Ntk virions and CoV-RBD121-NP (the virions after conjugation with the antigen). Yellow arrows indicate positions of conjugated antigen). Scale bar = 200 nm. (B) Size distribution of CoV-RBD121-NP at release and 1 and 3 months after storage at 2–8 °C. Distribution was calculated based on area under the curve (AUC) after analytical centrifugation. (C) Size distribution of CoV-RBD121-NP at 6 or 12 months after storage at 2–8 °C or 22–28 °C. Amount is shown as percentage of total based AUC analysis after ultracentrifugation.