Table 1.
Demographic and clinical characteristics of the study population.
| Variables | All | Increased Oxygen Demand | Nonincreased Oxygen Demand | p-Value | |
|---|---|---|---|---|---|
| Number of subjects, n | 79 | 45 | 34 | - | |
| Baseline characteristics | |||||
| Age, years | 62 [46, 77] | 65 [54, 77] | 51.5 [36, 71.5] | 0.025 | |
| Sex, male, % | 56 (70.9%) | 38 (84.4%) | 18 (52.9%) | 0.005 | |
| Height, cm | 168.5 [163.0, 177.8] | 173.0 [165.0, 179.0] | 164.4 [158.5, 169.3] | 0.008 | |
| Weight, kg | 65.0 [49.0, 74.9] | 67.0 [55.0, 80.0] | 56.5 [48.0, 70.0] | 0.052 | |
| Body mass index | 23.0 [20.8, 25.5] | 24.4 [21.6, 28.1] | 21.4 [19.1, 23.7] | 0.005 | |
| Onset to CT duration, days | 9.0 [6.0, 13.0] | 7.0 [5.0, 9.0] | 10.5 [8.3, 14.0] | 0.005 | |
| Status at the CT scan | |||||
| Oxygen demand, % | none | 56 (70.9%) | 26 (57.8%) | 30 (88.2%) | 0.173 |
| exist | 14 (12.7%) | 10 (22.2%) | 4 (11.8%) | ||
| no data | 9 (11.4%) | 9 (20.0%) | 0 (0.0%) | ||
| Mechanical ventilation, % | 1 (1.3%) | 1 (2.2%) | 0 (0.0%) | 1 | |
| Body temperature, °C | 37.0 [36.7, 37.9] | 37.6 [36.9, 38.0] | 36.7 [36.5, 37.1] | 0.001 | |
| WBC, 103/μL | 5500 [4025, 6900] | 5300 [3670, 6750] | 5600 [4550, 7250] | 0.313 | |
| LYM, % | 19.00 [10.60, 25.30] | 15.65 [9.28, 19.67] | 24.20 [18.15, 28.45] | 0.004 | |
| CRP, mg/dL | 4.96 [1.47, 11.97] | 9.92 [3.76, 15.59] | 2.13 [0.08, 7.88] | <0.001 | |
| LDH, U/L | 292.0 [219.0, 409.0] | 321.0 [284.0, 467.5] | 242.0 [191.5, 314.5] | 0.001 | |
| Lung volume, mL | 4197.2 [3424.6, 4895.8] | 4517.6 [3541.0, 5167.2] | 3828.0 [3352.1, 4575.8] | 0.059 | |
| Volume of opacity, mL | 446.3 [63.8, 767.0] | 585.3 [212.8, 916.1] | 132.8 [10.7, 456.1] | <0.001 | |
| Volume of high opacity, mL | 55.2 [8.2, 102.7] | 71.4 [27.0, 165.4] | 25.1 [0.9, 78.5] | 0.006 | |
| Volume of low opacity, mL | 336.2 [59.0, 655.1] | 440.3 [165.6, 718.0] | 95.1 [10.4, 405.6] | 0.001 | |
Continuous variables are expressed as median and interquartile range in brackets and were compared between the two groups using the Mann–Whitney U test. Categorical variables are expressed as numbers (%) and were compared between the groups using the χ2 test. Computed tomography, CT; white blood cell count, WBC; lymphocyte, LMY; C-reactive protein, CRP; lactate dehydrogenase, LDH; extracorporeal membrane oxygenation, ECMO.