Table 1.
Patients (Samples) | Hospitalized Patients (n = 10) | Convalescent Patients (n = 24) | Control Collective (n = 13) | p-Value | |
---|---|---|---|---|---|
Patient Characteristics | Age, years median (IQR) | 56.5 (54–63) | 56 (55–58) | 54 (51–57) | 0.08 |
Gender, male (%) | 10 (100) | 22 (91.6) | 4 (31) | 0.046 | |
BMI (IQR) | 23.8 (22–25.9) | 26.1 (22.8–28.1) | 22.3 (20.2–25.7) | 0.161 | |
Invasive Vent. (%) | 0 (0) | 0 (0) | 0 (0) | 1 | |
Oxygen therapy (%) | 0 (0) | 0 (0) | 0 (0) | 1 | |
Death (abs.) | 0 (0) | 0 (0) | 0 (0) | 1 | |
Interval 1. symptom to blood sample, days (IQR) | 6 (2–17) | 88 (70–135) | <0.001 | ||
SARS CoV-2 therapy | Remdesivir (5 days) | 1 (10) | 0 (0) | 0 (0) | 0.151 |
Dexamethasone (6 mg, 10 days) | 2 (20) | 0 (0) | 0 (0) | 0.021 | |
Pre-existing conditions | Chronic inflammatory disease (%) | 4 (40) | 0 (0) | 0 (0) | <0.001 |
Respiratory disease (%) | 3 (30) | 0 (0) | 0 (0) | 0.003 | |
Kidney insufficiency (%) | 1 (10) | 0 (0) | 0 (0) | 0.151 | |
Metastatic neoplasm (%) | 1 (10) | 0 (0) | 0 (0) | 0.151 | |
Diabetes (%) | 1 (10) | 0 (0) | 0 (0) | 0.151 | |
Arterial hypertension (%) | 4 (40) | 0 (0) | 0 (0) | <0.001 | |
Coronary heart disease (%) | 2 (20) | 0 (0) | 0 (0) | 0.021 | |
Medication | Angiotensin-1 receptor antagonist (%) | 1 (10) | 0 (0) | 0 (0) | 0.151 |
Angiotensin converting enzyme inhibitor (%) | 2 (10) | 0 (0) | 0 (0) | 0.021 |