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. 2021 Nov 19;22(22):12483. doi: 10.3390/ijms222212483

Figure 5.

Figure 5

The changes in Suv39H1 localization and levels in the neurons of ischemic penumbra 4 and 24 h after photothrombotic stroke in the rat cerebral cortex. The localisation and level of Suv39H1 are shown at 4 and 24 h after PTS (PTS4 and PTS24, respectively) compared to the contralateral cortex of the same animals (CL4 and CL24), or the cerebral cortex of sham-operated rats (SO). (a) Immunofluorescence of Suv39H1 (green), neuronal marker NeuN (red), nuclear chromatin marker Hoechst 33342 (blue), and image overlay. The scale bar is 50 μm. (b). Percent changes (ΔISO) of Suv39H1 levels in the penumbra at PTS4 or PTS24 and CL4 or CL24 compared to SO. (c) Percent changes (ΔICL) of Suv39H1 levels in the penumbra at PTS4 or PTS24 compared to the CL4 or CL24. (d) Coefficient M1 of Suv39H1 co-localization with the neuronal marker (NeuN) in different control and experimental groups. (e) Immunofluorescence of Suv39H1 in cell nuclei. (f) Percentage of cells expressing Suv39H1 per 100 cells stained with Hoechst 33342 * p < 0.05 compared to SO, # p < 0.05 compared to theCL4 or CL24. One Way ANOVA; M ± SEM; n = 7.