Table 1.
Biological Sample | Enzymatic Activity, 103 U/mg Protein | Level of the 20S Proteasome (α + β), RU | |
---|---|---|---|
ChTL | CL | ||
Breast tissues (all subtypes), T1–2N0–1M0 | |||
Cancer tissues, n = 80 |
45.6 [19.8; 92.3] * | 53.4 [18.4; 197.2] * | 0.72 [0.3; 2.5] |
Adjacent tissues, n = 80 |
19.8 [10.3; 42.1] | 17.7 [8.3; 43.6] | 1.0 [0.3; 3.1] |
Ovarian tissues, T3NxM0 | |||
Cancer tissues, n = 30 |
30.0 [26.0; 45.2] ** | 57.3 [13.6; 127.4] ** | 1.7 [0.8; 2.9] ** |
Normal tissues, n = 10 |
13.0 [7.8; 15.6] | 21.3 [11.2; 51.4] | 1.0 [0.5; 2.0] |
Note: Median and range value [25; 75%], RU–related units. * Significant differences with adjacent breast tissue, p < 0.05; ** Significant differences with normal ovarian tissue, p < 0.05.