Figure 5.

Genetic diversity of transcripts packaged in HML.2 GH and HML.2 Tera-1 particles. Analyses of type 2 env genes. Neighbor-joining phylogenetic analysis of 460 bp env cloned sequences. Viral RNA was extracted from gradient fractions with buoyant density 1.16 g/cm³. Twenty-five sequences from HML.2 GH (red) and from HML.2 Tera-1 (green), and nineteen reference sequences (black) were used for alignment. Cloned sequences formed five clades. HML.2 Tera-1 contained HERV-K 108 env and closely related sequences (Clade 5), while HML.2 GH packaged diverse env (Clades 1–5).