Table 1.
Study | EG/CG | BCI modality | Experimental intervention | Control intervention | Intervention period | Feature | Stroke phase | MI/IM | Outcome measures | Follow-up (weeks) |
---|---|---|---|---|---|---|---|---|---|---|
Ang et al 37 | 6/8 HK/7SAT | EEG | BCI-HK 1 h BCI + 30 min TAAM | HK:1 h HK + 30 min TAAM; SAT:1.5 h TAAM | 6 weeks, 18 sessions | FBCSP | Chronic | MI | FMA-UE | 24 |
Ang et al 9 | 11/14 | EEG | BCI-MIT-Manus robot 1.5 h 136 repetitions | MIT-Manus robot 1.5 h 1040 repetitions | 4 weeks, 12 sessions | FBCSP | Chronic | MI | FMA-UE | 12 |
Ang et al. 10 | 10/9 | EEG | 20 min tDCS + 1 h BCI- MIT-Manus robot | 20 min sham tDCS + 1 h sham BCI | 2 weeks, 10 sessions | FBCSP | Chronic | MI | FMA-UE | 4 |
Biasiucci et al 17 | 14/13 | EEG | BCI-FES 1 h | Sham BCI-FES 1 h | 5 weeks, 10 sessions | Band power | Chronic | IM | FMA-UE, ESS, MRC, MAS | 36 |
Cheng et al 42 | 5/5 | EEG | BCI-assisted soft robotic glove 90 min + 30 min SAT | Soft robotic glove 90 min + 30 min SAT | 6 weeks, 18 sessions | FBCSP | Chronic | MI | FMA-UE, ARAT | 24 |
Frolov et al 39 | 36/11 | EEG | BCI-exoskeleton 30 min + SPT | Sham BCI 30 min | 2 weeks, 10 sessions | Band power | Chronic | MI | FMA-UE, ARAT | N/A |
Kim et al 40 | 15/15 | EEG | BCI-FES 30 min + 30 min AOT | AOT 30 min | 4 weeks, 12 sessions BCI. 20 sessions AOT | Band power | Chronic | IM | FMA-UE, MAL, MBI | N/A |
Li et al 8 | 7ne;7nc | EEG | BCI-FES 1–1.5 h + CON | FES 20 min + CON | 8 weeks, 24 sessions BCI/FES and 40 sessions CON | CSP | Subacute | MI | FMA-UE, ARAT | N/A |
Mihara et al 12 | 10/10 | fNIRS | BCI-visual feedback 20 min + 120 min NDT | Sham BCI 20 min + 120 min NDT | 2 weeks, 6 sessions BCI/Sham, 14 sessions NDT | Band power | Subacute | MI | FMA-UE, ARAT, MAL | 2 |
Pichiorri et al 41 | 14/14 | EEG | BCI-virtual hand 1 h | MI, 1 h | 4 weeks, 12 sessions | Band power | Subacute | MI | FMA-UE | N/A |
Ramos-Murguialday et al 11 | 16/16 | EEG | BCI-orthosis 1 h + 1 h BPT | Sham BCI-orthosis 1 h + 1 h BPT | 4 weeks, 20 sessions | Band power | Chronic | IM | FMA-UE GAS, MAL | 26 |
Wu et al 13 | 14/11 | EEG | BCI-exoskeleton 1 h + 1 h routine training | Routine training 2 h | 4 weeks, 20 sessions | Band power | Subacute | MI | FMA-UE ARAT, WMFT | N/A |
Abbreviations: AOT, action observational training; ARAT, action research arm test; BCI, brain–computer Interface; BPT, behavioral physical therapy; CG, control group; CON, conventional therapy; CSP, common spatial pattern; EG, experimental group; EES, European stroke scale score; GAS, goal attainment scale; FBCSP, filter bank common spatial pattern; fNIRS, functional near-infrared spectroscopy; FES, functional electrical stimulation; FMA-UE, Fugl-Meyer assessment upper extremity; IM, intention of movement; HK, haptic knob; MAL, motor activity long; MAS, modified Ashworth scale; MBI, modified Barthel index; MI, motor imagery; MRC, medical research council; N/A, not available; NDT, neurodevelopmental treatment; SAT, standard activity therapy; SPT, standard physical therapy; TAAM, therapist-assisted arm mobilization; tDCS, transcranial direct-current stimulation; WMFT, Wolf motor function test.