Fig. 3.
a–d Effect of plasma treatment over 7 days on the 4 HSI parameters (NIR, StO2, THI, and TWI) of acute skin wounds. Patients with acute split skin graft donor site wounds were treated for 7 days with a conventional wound dressing and a CAP applying dressing on comparably large areas of the wound. Every other day, HSI measured parameter indices (scale 1–100) on both areas. Statistics were analyzed using a linear mixed model on each day separately (*p < 0.05; **p < 0.01; ***p < 0.001). CAP, cold atmospheric plasma; HSI, hyperspectral imaging; NIR, near-infrared perfusion; StO2, superficial hemoglobin oxygen saturation; THI, tissue hemoglobin index; TWI, tissue water index.