Table 1.
Descriptive Characteristic | NBC Participants Included in Main Analysis, n = 373 | NBC Participants not Included in Main Analysis, n = 415 | |||||
---|---|---|---|---|---|---|---|
Inhibition Measures 2 | n (%) | Mean (SD) | Range | n (%) | Mean (SD) | Range | p -Value 3 |
Design Fluency | |||||||
Total number correct scaled score | 373 | 9.6 (2.7) | 2–17 | 155 | 9.3 (3) | 1–19 | 0.3 |
Total number errors raw score | 373 | 2.2 (2.7) | 0–19 | 155 | 2.6 (3.5) | 0–30 | 0.1 |
Color–Word Interference scores | |||||||
Completion time scaled score | 373 | 9.9 (2.8) | 1–16 | 154 | 9.8 (2.7) | 1–14 | 0.6 |
Total number errors raw score | 373 | 2.3 (2.5) | 0–19 | 154 | 2.3 (2.3) | 0–12 | 0.7 |
Overall performance | |||||||
Best performance | 117 (31.4) | 37 (8.9) | 0.1 | ||||
Poor performance | 256 (68.6) | 117 (28.2) | |||||
Missing | 0 | 261 (62.9) | |||||
Exposure Measures 4 | |||||||
Cord serum DDE (ng/g) | 373 | 0.6 (1.2) | 0.02–14.9 | 378 | 0.4 (0.4) | 0.0–4.2 | <0.01 * |
Cord serum HCB (ng/g) | 373 | 0.03 (0.02) | 0.0–0.1 | 378 | 0.03 (0.05) | 0.0–0.7 | 0.1 |
Cord serum ΣPCB4 (ng/g) | 373 | 0.3 (0.3) | 0.01–4.4 | 378 | 0.2 (0.2) | 0.01–1.9 | 0.05 |
Cord blood Pb (μg/dL) | 373 | 1.4 (0.9) | 0–9.4 | 375 | 1.7 (1.7) | 0.0–17.4 | <0.01 * |
Cord blood Mn (µg/dL) | 373 | 4.2 (1.6) | 0.7–14.6 | 335 | 4.3 (2.0) | 0.2–22.1 | 0.6 |
Covariate Measures 5 | |||||||
Child Characteristics | |||||||
Race/Ethnicity | 0.09 | ||||||
Non-Hispanic White | 263 (70.5) | 268 (64.6) | |||||
Hispanic | 33 (8.8) | 56 (13.5) | |||||
Other | 77 (20.6) | 89 (21.4) | |||||
Missing | 0 | 2 (0.5) | |||||
Sex | 0.05 | ||||||
Male | 179 (48.0) | 229 (55.2) | |||||
Female | 194 (52.0) | 186 (44.8) | |||||
Age at Exam | 373 | 15.5 (0.6) | 14.4–17.8 | 155 | 15.7 (0.7) | 13.9–17.9 | <0.01 * |
Home Score | 373 | 43.9 (6.3) | 21–56 | 118 | 42.7 (6.0) | 27–53 | 0.07 |
Year of birth | |||||||
1993–1994 | 100 (26.8) | 159 (38.3) | <0.01 * | ||||
1995–1996 | 153 (41.0) | 147 (35.4) | |||||
1997–1998 | 120 (32.2) | 109 (26.3) | |||||
Maternal Characteristics | |||||||
Marital status at birth | <0.01 * | ||||||
Not married | 136 (36.5) | 195 (47.0) | |||||
Married | 237 (63.5) | 165 (39.8) | |||||
Missing | 0 | 55 (13.3) | |||||
Maternal IQ | 373 | 99.4 (10.4) | 57–124 | 262 | 95.8 (10.2) | 72–126 | <0.01 * |
Seafood during pregnancy (serv/day) | 373 | 0.5 (0.6) | 0–5.3 | 260 | 0.6 (0.7) | 0–6 | 0.6 |
Smoking during pregnancy | 0.1 | ||||||
No | 272 (72.9) | 210 (50.6) | |||||
Yes | 101 (27.1) | 103 (24.8) | |||||
Missing | 0 | 102 (24.6) | |||||
Household Characteristics at Birth | |||||||
Maternal education | <0.01 * | ||||||
≤High School | 190 (50.9) | 231 (55.7) | |||||
>High School | 183 (49.1) | 127 (30.6) | |||||
Missing | 0 | 57 (13.7) | |||||
Paternal Education | <0.01 * | ||||||
≤High School | 246 (66.0) | 266 (64.1) | |||||
>High School | 127 (34.0) | 81 (19.5) | |||||
Missing | 0 | 68 (16.4) | |||||
Annual Household Income | <0.01 * | ||||||
<USD 20,000 | 115 (30.8) | 150 (36.1) | |||||
≥USD 20,000 | 258 (69.2) | 201 (48.4) | |||||
Missing | 0 | 64 (15.4) | |||||
Examination Characteristics | |||||||
Examiner | 0.4 | ||||||
1 | 277 (74.3) | 121 (29.2) | |||||
2 | 96 (25.7) | 34 (8.2) | |||||
Missing | 0 | 260 (62.7) |
1 Main analysis group (Set 1): complete inhibition outcome, covariate, and exposure data for, DDE, HCB, ΣPCB4, Pb and Mn, n = 373. 2 NBC participants with missing inhibition measures: Design Fluency total correct n = 260, total errors n = 260; Color–Word Interference completion time n = 261, total errors n = 261.3 P-values represent results comparing characteristics between participants included in Set 1 and those excluded from Set 1 using t-tests, Wilcoxon rank sum tests, and chi-square tests. P-values reflect comparisons based on non-missing data. 4 NBC participants with missing exposure measures: DDE n = 37; HCB n = 37; ΣPCB4 n = 37; Pb n= 40; Mn n = 80. 5 NBC participants with missing covariate measures: age at exam n = 260; HOME score n= 297; maternal IQ n = 153; seafood during pregnancy n= 155. * p < 0.05. Abbreviations: DDE: dichlorodiphenyldichloroethylene; HCB: hexachlorobenzene; ΣPCB4: sum of 4 PCB congeners (118, 138, 153, 180); Pb: lead; Mn: manganese.