Table 2.
Complete-case results of multivariable linear regression analyses (difference in scaled scores associated with a twofold increase in exposure and 95% CI) 1 assessing the relation of prenatal exposure to a five-chemical mixture with Delis–Kaplan Executive Function System inhibition scaled scores among adolescents in the main analysis group 2.
| Exposure | Design Fluency Total Correct Scaled Score Difference (95% CI) |
Color–Word Interference Completion Time Scaled Score Difference (95% CI) |
|---|---|---|
| Log2 DDE | 0.00 (−0.32, 0.33) | 0.09 (−0.22, 0.40) |
| Log2 HCB | 0.04 (−0.28, 0.36) | −0.08 (−0.42, 0.25) |
| Log2 ΣPCB4 | −0.15 (−0.49, 0.18) | −0.24 (−0.59, 0.10) |
| Log2 Pb | −0.05 (−0.35, 0.26) | 0.07 (−0.25, 0.39) |
| Log2 Mn | 0.91 (−0.02, 1.84) | −0.74 (−1.34, −0.14) * |
| Log2 Mn2 | −0.59 (−1.49, 0.30) | |
| Log2 DDE Log2 Mn | 0.53 (0.05, 1.01) * | |
| Log2 DDE Log2 Mn2 | 0.03 (−0.52, 0.58) |
1 Exposures have been log2-transformed and models have been adjusted for all listed exposures, child race, sex, age at exam, year of birth, and HOME score; maternal marital status at child’s birth, IQ, seafood consumption during pregnancy, and smoking during pregnancy; maternal and paternal education and annual household income at child’s birth; study examiner. 2 Main analysis group: complete inhibition outcome, covariate and exposure data for DDE, HCB, ΣPCB4, Pb and Mn, n = 373. * p < 0.05. Abbreviations: DDE: dichlorodiphenyldichloroethylene; HCB: hexachlorobenzene; ΣPCB4: sum of 4 PCB congeners (118, 138, 153, 180); Pb: lead; Mn: manganese.