Table 5.
Complete-case results of negative binomial regression analyses (rate ratio and 95% CI) 1 assessing the relation of prenatal exposure to a five-chemical mixture with Delis–Kaplan Executive Function System (D-KEFS) inhibition error raw scores among adolescents in the main analysis group 2.
| Exposure | Design Fluency Total Errors Rate Ratio (95% CI) |
Color–Word Interference Total Errors Rate Ratio (95% CI) |
|---|---|---|
| Log2 DDE | 1.04 (0.92, 1.17) | 0.91 (0.82, 1.02) |
| Log2 HCB | 1.08 (0.95, 1.24) | 1.07 (0.95, 1.21) |
| Log2 ΣPCB4 | 0.94 (0.82, 1.08) | 1.13 (1.00, 1.28) |
| Log2 Pb | 1.00 (0.88, 1.13) | 0.91 (0.82, 1.02) |
| Log2 Mn | 0.78 (0.61, 0.99) * | 1.10 (0.88, 1.36) |
1 Exposures have been log2-transformed and models have been adjusted for child race, sex, age at exam, year of birth, and HOME score; maternal marital status at child’s birth, IQ, seafood consumption during pregnancy, and smoking during pregnancy; maternal and paternal education and annual household income at child’s birth; and study examiner. 2 Main analysis group: complete inhibition outcome, covariate and prenatal exposure biomarker data for DDE, HCB, ΣPCB4, Pb and Mn, n = 373. * p < 0.05. Abbreviations: DDE: dichlorodiphenyldichloroethylene; HCB: hexachlorobenzene; ΣPCB4: sum of 4 PCB congeners (118, 138, 153, 180); Pb: lead; Mn: manganese.