Table 6.
Complete-case results of logistic regression analyses (odds ratio and 95% CI) 1 assessing the relation of prenatal exposure to a five-chemical mixture with odds of poor Delis–Kaplan Executive Function System (D-KEFS) Color–Word Interference: Inhibition overall performance among adolescents in the main analysis group 2.
| Exposure | Color–Word Interference Overall Performance Odds Ratio (95% CI) |
|---|---|
| Best performance: n = 117 | |
| Poor performance: n = 256 | |
| Log2 DDE | 0.93 (0.70, 1.22) |
| Log2 HCB | 1.22 (0.93, 1.60) |
| Log2 ΣPCB4 | 1.16 (0.87, 1.55) |
| Log2 Pb | 0.79 (0.59, 1.05) |
| Log2 Mn | 1.61 (0.98, 2.64) |
1 Exposures have been log2-transformed and models have been adjusted for child race, sex, age at exam, year of birth, and HOME score; maternal marital status at child’s birth, IQ, seafood consumption during pregnancy, and smoking during pregnancy; maternal and paternal education and annual household income at child’s birth; and study examiner. 2 Main analysis group: complete outcome, covariate and prenatal exposure biomarker data for DDE, HCB, ΣPCB4, Pb and Mn, n = 373. Abbreviations: DDE: dichlorodiphenyldichloroethylene; HCB: hexachlorobenzene; ΣPCB4: sum of 4 PCB congeners (118, 138, 153, 180); Pb: lead; Mn: manganese.