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. 2021 Nov 12;11(11):2089. doi: 10.3390/diagnostics11112089

Table 1.

Demographic and Clinical characteristics of 53 enrolled patients.

All Patients
(n = 53)
Urinary SARS-CoV-2 p Value Illness Severity p Value
URNA
(n = 38, 71.7%)
URNA+
(n = 15, 28.3%)
URNA
vs.
URNA+
Non-Severe Severe S URNA+
vs.
S URNA
URNA
(n = 26, 86.7%)
URNA+
(n = 4, 13.3%)
URNA
(n = 12, 52.2%)
URNA+
(n = 11, 47.8%)
Demographic characteristic (No., %)
Age, years 52
(42.0–66.0)
51.0
(38.3–59.8)
61.0
(48.5–72.0)
0.016 50.5
(37.3–56.8)
50.0
(48.5–60.8)
55.0
(51.0–63.5)
66.0
(50.0–72.0)
0.126
Female 31/53 (58%) 22/38 (58%) 9/15 (60%) 0.889 17/26 (65%) 3/4 (75%) 5/12 (42%) 6/11 (55%) 0.684
Respiratory symptoms (No., %)
Fever 41/53 (77.4%) 31/38 (73.7%) 13/15 (86.7%) 0.969 16/26 (61.5%) 4/4 (100.0%) 12/12 (100.0%) 9/11 (81.8%) 0.217
Cough 38/53 (71.7%) 31/38 (73.7%) 10/15 (66.7%) 0.421 19/26 (73.1%) 3/4 (75.0%) 9/12 (75.0%) 7/11 (63.6%) 0.667
Sputum production 13/53 (24.5%) 9/38 (23.7%) 6/15 (40.0%) 0.396 5/26 (19.2%) 3/4 (75.0%) 2/12 (16.7%) 3/11 (27.3%) 0.640
Fatigue 18/53 (34.0%) 11/38 (29.0%) 7/15 (46.7%) 0.220 9/26 (34.6%) 3/4 (75.0%) 2/12 (16.7%) 4/11 (36.4%) 0.371
Chest tightness 14/53 (26.4%) 6/38 (15.8%) 9/15 (60.0%) 0.001 3/26 (11.5%) 3/4 (75.0%) 2/12 (16.7%) 6/11 (54.6%) 0.089
Shortness of breath 19/53 (35.9%) 12/38 (31.6%) 10/15 (66.7%) 0.02 0/26 (0.0%) 0/4 (0.0%) 9/12 (75.0%) 10/11 (90.9%) 0.590
Radiological appearance (No., %)
Unilateral pneumonia 2/53 (3.77%) 2/38 (5.3%) 0/15 (0.0%) 0.365 2/26 (7.7%) 0/4 (0.0%) 0/12 (0.0%) 0/11 (0.0%) UTC
Bilateral pneumonia 35/53 (66.0%) 26/38 (68.4%) 9/15 (60.0%) 0.560 17/26 (62.4%) 1/4 (25.0%) 9/12 (75.0%) 8/11 (72.7%) 1.000
Multiple “ground-glass opacity” lesions 20/35 (37.7%) 17/38 (44.7%) 3/15 (20.0%) 0.094 14/26 (53.9%) 0/4 (0.0%) 3/12 (25.0%) 3/11 (27.3%) 1
Comorbidities (No., %)
Hypertension 19/53 (35.9%) 11/38 (29.0%) 8/15 (53.3%) 0.095 9/26 (34.6%) 0/4 (0.0%) 2/12 (16.7%) 8/11 (72.7%) 0.012
Diabetes 7/53 (13.2%) 5/38 (13.2%) 2/15 (13.3%) 0.986 3/26 (11.5%) 0/4 (0.0%) 2/12 (16.7%) 2/11 (18.2%) 1.000
Cardiovascular diseases 6/53 (11.3%) 2/38 (5.3%) 4/15 (26.7%) 0.083 2/26 (7.7%) 0/4 (0.0%) 0/12 (0.0%) 4/11 (36.4%) 0.037
Chronic renal disease 2/53 (3.8%) 2/38 (5.3%) 0/15 (0.0%) 0.365 2/26 (7.7%) 0/4 (0.0%) 0/12 (0.0%) 0/11 (0.0%) UTC
In-hospital death (No., %) 6/53 (11.3%) 2/38 (5.3%) 4/15 (26.7%) 0.083 0/26 (0.0%) 0/4 (0.0%) 2/12 (16.7%) 4/11 (36.4%) 0.371

Data shown as medians (interquartile ranges, IQR) and numbers/total (%); UTC, unable to calculate; URNA, negative urinary SARS-CoV-2; URNA+, positive urinary SARS-CoV-2; S, Severe. p values presented the comparison between Negative cases and positive cases. p < 0.05 was considered statistically significant.