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. 2021 Oct 27;13(11):1800. doi: 10.3390/pharmaceutics13111800

Table 2.

Antibacterial activities of antimicrobial peptides and antibiotics against microorganisms.

Peptides Minimum Inhibitory Concentration (μg·mL−1)
Gram-Negative Bacteria Gram-Positive Bacteria
E. coli A. baumanii CRAB C1 CRAB C2 CRAB C3 CRAB C4 CRAB C5 GM 1 S.aureus
PapMA 32 32 32 32 16 64 32 34 64
PapMA-2 64 128 128 >128 64 >128 128 146 >128
PapMA-3 16 16 16 16 16 32 16 18 32
PapMA-4 16 8 8 8 8 16 8 10 32
PapMA-5 16 16 16 16 16 32 16 18 32
PapMA-6 16 8 8 8 8 16 16 11 32
melittin 8 16 16 16 16 8 16 14 16
Antibiotics
Imipenem 0.25 0.25 64 64 64 64 64 46 1
Meropenem 0.25 0.25 128 64 64 128 64 64 1
Rifampin 2 4 128 64 128 128 256 101 1
Erythromycin 16 32 >512 512 512 >512 >512 592 0.25
Vancomycin 128 256 256 256 256 512 256 274 0.5
Linezolid 256 256 256 256 256 512 512 329 1

1 The geometric means (GMs) are the mean minimum inhibitory concentration (MIC) values of Gram-negative bacterial strains. The GMs were assumed to be 256 μg·mL1 for MIC > 128 μg·mL1 and 1024 μg·mL1 for MIC > 512 μg·mL1.