Table 2.
Peptides | Minimum Inhibitory Concentration (μg·mL−1) | ||||||||
---|---|---|---|---|---|---|---|---|---|
Gram-Negative Bacteria | Gram-Positive Bacteria | ||||||||
E. coli | A. baumanii | CRAB C1 | CRAB C2 | CRAB C3 | CRAB C4 | CRAB C5 | GM 1 | S.aureus | |
PapMA | 32 | 32 | 32 | 32 | 16 | 64 | 32 | 34 | 64 |
PapMA-2 | 64 | 128 | 128 | >128 | 64 | >128 | 128 | 146 | >128 |
PapMA-3 | 16 | 16 | 16 | 16 | 16 | 32 | 16 | 18 | 32 |
PapMA-4 | 16 | 8 | 8 | 8 | 8 | 16 | 8 | 10 | 32 |
PapMA-5 | 16 | 16 | 16 | 16 | 16 | 32 | 16 | 18 | 32 |
PapMA-6 | 16 | 8 | 8 | 8 | 8 | 16 | 16 | 11 | 32 |
melittin | 8 | 16 | 16 | 16 | 16 | 8 | 16 | 14 | 16 |
Antibiotics | |||||||||
Imipenem | 0.25 | 0.25 | 64 | 64 | 64 | 64 | 64 | 46 | 1 |
Meropenem | 0.25 | 0.25 | 128 | 64 | 64 | 128 | 64 | 64 | 1 |
Rifampin | 2 | 4 | 128 | 64 | 128 | 128 | 256 | 101 | 1 |
Erythromycin | 16 | 32 | >512 | 512 | 512 | >512 | >512 | 592 | 0.25 |
Vancomycin | 128 | 256 | 256 | 256 | 256 | 512 | 256 | 274 | 0.5 |
Linezolid | 256 | 256 | 256 | 256 | 256 | 512 | 512 | 329 | 1 |
1 The geometric means (GMs) are the mean minimum inhibitory concentration (MIC) values of Gram-negative bacterial strains. The GMs were assumed to be 256 μg·mL−1 for MIC > 128 μg·mL−1 and 1024 μg·mL−1 for MIC > 512 μg·mL−1.