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. 2021 Oct 27;11(11):1147. doi: 10.3390/life11111147

Figure 1.

Figure 1

Genomic organization and protein structure of PRMT1. (A) Genomic organization of the PRMT1 gene which spans 11.3 kilobases (kb) and possesses 12 constitutive exons including exon 1 subdivided into 4 alternative exons, represented by a scale of blue-colored boxes; (B) Exon composition of the different PRMT-1 isoforms (v1 to v7). The sequences of intron boundaries are represented by the black boxes. Molecular weight of each protein isoform is indicated in kilodaltons (kDa); (C) Protein structure of PRMT1-v2. The PRMT signature motifs (I, Post-I (PI), II, III) as well as double-E motif, the THW loop and the phosphorylation site Y291 are represented (adapted from [5,6]).