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Oncogenesis signaling of basal cell carcinoma and possible roles of omega-3 PUFAs. As the detailed oncogenesis of basal cell carcinoma, hedgehog pathway gene mutation activates patched homolog and smoothened homolog, which are responsible for the development of basal cell carcinoma. P53 is suppressed by ultraviolet light exposure, leading to the suppression of apoptosis of basal cell carcinoma.
