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. 2021 Nov 10;22(22):12163. doi: 10.3390/ijms222212163

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Expression profiles of TNF-α and IL-17A in serum during PIA. (A) Expression profile of TNF-α in serum. (B) Expression profile of IL-17A in serum. Both profiles are evaluated with ELISA in serum from male and female DA rats: control (treated with saline); PIA onset (between 9th and 12th day after induction); PIA peak (between 16th and 20th day after induction); PIA remission (between 20th and 25th day after induction). Values in pg/mL are expressed as mean ± SD (10 rats/group, N = 40). One-way ANOVA followed by the post hoc Scheffé test: * p < 0.05, ** p < 0.01, and *** p < 0.001.