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Potential and well-known risk factors for CRS in childhood.
| Inflammation/Infections | Systemic Diseases | Local Factors |
|---|---|---|
| Recurrent upper respiratory tract infections | Cystic fibrosis | Small sinus ostia |
| Developing immune system | Primary ciliary dyskinesia | Anatomic variations |
| Adenoid hypertrophy | Immunodeficiencies | Traumas |
| Allergic and non-allergic rhinitis | Vasculitis | Foreign bodies |
| Tobacco smoke exposure | ||
| Environmental pollution | ||
| Gastro-esophageal reflux disease |
