A375	Malignant melanoma skin cancer
C. annuum L.	Capsicum annuum Linnaeus
CAP	Capsaicin
DDs	Drug Delivery Systems
DLS	Dynamic Light Scattering
DMSO	Dimethyl Sulfoxide
DPPC	1,2-Dipalmitoyl-sn-glycero-3-phosphocholine
DSC	Differential Scanning Calorimetry
DSPE-PEG2000	1, 2-Distearoyl-sn-glycero-3-phosphoethanolamine-NPEG2000
EE	Encapsulation Efficiency
EGFR	Epidermal growth factor receptor
EMEM	Eagle’s Minimum Essential Medium
FBS	Fetal bovine serum
FDA	Food and Drug Administration
HPLC	High performance liquid chromatography
H0	Null hypothesis
Ha	Null hypothesis
IC50	Half maximal inhibitory concentration
k562	Myelogenous leukemia cancer cell line
LLOD	Lower limit of Detection
LLOQ	Lower limit of Quantitation
MCF-7	Breast cancer cell line, Michigan Cancer Foundation-7
MDA-MB-231	Triple-negative breast cancer (TNBC)
MEM	Minimum Essential Medium
MTT	3-(4,5-Dimethyl-2-thiazolyl)-2,5-diphenyltetrazolium Bromide solution
NP	Nanoparticles
PBS	Phosphate Buffered Saline
PANC1	Pancreas cancer
PDI	Polydispersity Index
RPMI	RPMI 1640 growth medium
TEM	Transmission Electron Microscopy
TRPV1	The transient receptor potential cation channel subfamily V member 1
Z	Zeta