Table 1.
Disperse characteristics of doxorubicin-free and doxorubicin-containing microbeads and microcapsules with different structures.
Sample * | Size, µm ** | ζ-Potential, mV |
---|---|---|
DOX-free MBs | 2.5 ± 07 | −17.2 ± 0.8 |
DOX-free MCs | 2.0 ± 0.4 | −20.4 ± 2.2 |
DOX-containing MBs | 2.0 ± 0.4 | −12.5 ± 1.7 |
DOX-containing MCs(8L) | 2.4 ± 0.6 | −7.5 ± 2.2 |
DOX-containing MBs(+8L) | 2.0 ± 0.8 | −23.5 ± 2.4 |
* MBs, calcium carbonate microbeads; MCs, microcapsules; 8L, the number of assembled polyelectrolyte layers (PAH/PSS)4; DOX, doxorubicin; ** the size was estimated using optical microscopy. The microbeads and microcapsules with different structures did not differ significantly from one another in size (p > 0.05, Student’s t-test).