Table 1.

Main enzymes involved in drug metabolism in forensic toxicology.

Drugs of Toxicological Interest and Their Metabolizing Enzymes [22,23,24]
Gene Involved in Drug Metabolization	Drugs Metabolized
CYP2C19	Amitriptylineim, Ipramine, Diazepam, Citalopram, Carisoprodol, several Anticonvulsants
CYP2D6	Amphetamines, Codeine, Oxycodone, Hydrocodone, Methadone, Tramadol, some Antipsychotics, some Tricyclic Antidepressants, Steroids
CYP3A4	Benzodiazepines, Fentanyl, Methadone, Buprenorphine, Hypnotics, some Antipsychotics, some Tricyclic Antidepressants
CYP2E1	Ethanol, some Anaesthetics, Paracetamol, Verapamil