Table 2.
Disease genes from the “psychiatric disease” family and related disorders.
| Gene Symbol | Gene Name | Disease |
|---|---|---|
| ATP4B | ATPase H+/K+ transporting beta subunit | Bipolar Disorder |
| FAT4 | FAT atypical cadherin 4 | Bipolar Disorder |
| FKBP5 | FK506 binding protein 5 | Depression, affective psychoses, post-traumatic stress disorder, bipolar disorders |
| RASIP1 | Ras interacting protein 1 | Bipolar Disorder |
| ADRA1D | Adrenoceptor alpha 1D | Several psychiatric disorders |
| AHR | Aryl hydrocarbon receptor | Dementia |
| C1GALT1 | Core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 | Bipolar Disorder |
| CBS | Cystathionine-beta-synthase | Dementia (AD), migraine disorders, schizophrenia |
| DAP | Death-associated protein | Schizophrenia |
| GABRA6 | Gamma-aminobutyric acid type A receptor alpha-6-subunit | Schizophrenia, anxiety disorder |
| ID2 | Inhibitor of DNA binding 2, HLH protein | Attention-deficit hyperactivity disorder |
| INSIG2 | Insulin-induced gene 2 | Schizophrenia |
| MASP2 | Mannan binding lectin serine peptidase 2 | Dementia |
| NTSR1 | Neurotensin receptor 1 | Schizophrenia, several psychiatric disorders |
| NTRK1 | Neurotrophic receptor tyrosine kinase 1 | Several psychiatric disorders, autism, dementia |
| NR4A1 | Nuclear receptor subfamily 4 group A member 1 | Schizophrenia, bipolar disorder |
| NR4A3 | Nuclear receptor subfamily 4 group A member 3 | Schizophrenia, bipolar disorder |
| NUDT6 | Nudix hydrolase 6 | Schizophrenia, bipolar disorder |
| OLIG2 | Oligodendrocyte lineage transcription factor 2 | Schizophrenia, obsessive compulsive disorder, Tourette syndrome, dementia |
| PDE9A | Phosphodiesterase 9A | Depression |
| PLCD4 | Phospholipase C delta 4 | Several psychiatric disorders |
| PAQR5 | Progestin and adipoQ receptor family member 5 | Mental Disorders |
| SSTR2 | Somatostatin receptor 2 | Several psychiatric disorders |
| SSTR3 | Somatostatin receptor 3 | Several psychiatric disorders |
| SPRY4 | Sprouty RTK signaling antagonist 4 | Schizophrenia |
| SYT6 | Synaptotagmin 6 | Mental Disorders |
| TRPV1 | Transient receptor potential cation channel subfamily V member 1 | Autism |
| VEGFA | Vascular endothelial growth factor A | Major depressive disorder, autism, dementia |
| ZBED4 | Zinc finger BED-type containing 4 | Schizophrenia, bipolar disorder |