TABLE 2.
Antimicrobial susceptibility testing of B. hinzii and B. avium by three methods
| Antibiotica | Method | Susceptibilityb
|
|||
|---|---|---|---|---|---|
| B. hinzii BC-306 | B. hinzii LMG13501T | B. hinzii BC-305 | B. avium ATCC 35086T | ||
| Ampicillin* | Disk | R (9) | R (13) | R (11) | S (30) |
| Ampicillin* | E-test | I (16) | I (16) | I (16) | S (0.5) |
| Ampicillin* | Micro brothc | R (32) | R (32) | R (32) | S (<1) |
| Ampicillin-sulbactam | Disk | R (11) | I (14) | I (14) | S (33) |
| Ampicillin-sulbactam | E-test | I (16/8) | I (16/8) | I (16/8) | S (0.5) |
| Ampicillin-sulbactam | Micro broth | I (16/8) | R (32/16) | R (32/16) | S (<2/1) |
| Amoxicillin-clavulanic acid* | Disk | I (17) | S (21) | S (20) | S (34) |
| Amoxicillin-clavulanic acid* | E-test | R (32) | R (16) | R (16) | S (0.5) |
| Ticarcillin | Disk | I (17) | S (21) | S (20) | S (36) |
| Ticarcillin | Micro broth | I (32) | I (32) | I (64) | S (<4) |
| Ticarcillin-clavulanic acid | Disk | S (21) | S (23) | S (23) | S (36) |
| Ticarcillin-clavulanic acid | E-test | I (32) | I (32) | I (64) | S (0.75) |
| Ticarcillin-clavulanic acid | Micro broth | S (16) | S (16) | S (16) | S (<4) |
| Piperacillin | Disk | S (35) | S (37) | S (36) | S (37) |
| Piperacillin | Micro broth | S (<4) | S (<4) | S (<4) | S (<4) |
| Piperacillin-tazobactam | Disk | S (35) | S (37) | S (36) | S (38) |
| Piperacillin-tazobactam | E-test | S (1) | S (1) | S (1) | S (1) |
| Piperacillin-tazobactam | Micro broth | S (<4/4) | S (<4/4) | S (<4/4) | S (<4/4) |
| Cefazolin* | Disk | R (10) | R (10) | R (13) | I (17) |
| Cephalotin* | Disk | S (22) | S (24) | S (25) | S (31) |
| Cefotetan* | Disk | R (6) | R (6) | R (6) | S (20) |
| Cefuroxime* | Disk | R (6) | R (6) | R (6) | I (16) |
| Ceftriaxone | Disk | I (14) | R (13) | I (15) | S (28) |
| Ceftriaxone | E-test | R (64) | R (64) | R (64) | S (4) |
| Ceftriaxone | Micro broth | I (32) | I (32) | I (32) | S (2) |
| Cefotaxime | Micro broth | I (32) | I (32) | I (32) | S (2) |
| Ceftazidime | Disk | S (26) | S (26) | S (27) | S (31) |
| Ceftazidime | E-test | S (4) | S (4) | S (4) | S (2) |
| Ceftazidime | Micro broth | S (2) | S (2) | S (2) | S (<1) |
| Cefepime | Disk | S (25) | S (27) | S (27) | S (30) |
| Cefepime | E-test | S (8) | S (8) | S (8) | S (4) |
| Cefepime | Micro broth | S (4) | S (4) | S (4) | S (2) |
| Imipenem | Disk | S (30) | S (30) | S (30) | S (26) |
| Imipenem | E-test | S (2) | S (2) | S (2) | S (2) |
| Imipenem | Micro broth | S (1) | S (1) | S (1) | S (1) |
| Aztreonam | Disk | R (6) | R (6) | R (6) | I (17) |
| Aztreonam | Micro broth | R (32) | R (>32) | R (32) | I (16) |
| Chloramphenicol | Disk | R (10) | I (13) | R (10) | S (2) |
| Tetracycline | Disk | S (19) | S (25) | S (25) | S (32) |
| Trimethoprim-sulfamethoxazole | Disk | S (33) | S (34) | S (35) | S (35) |
| Trimethoprim-sulfamethoxazoled | E-test | S (0.047) | S (0.047) | S (0.023) | S (0.047) |
| Ciprofloxacin | Disk | I (17) | I (19) | I (18) | S (23) |
| Ciprofloxacin | E-test | R (4) | R (4) | R (4) | I (2) |
| Ciprofloxacin | Micro broth | I (2) | I (2) | I (2) | S (1) |
| Levofloxacin | Disk | S (20) | S (23) | S (22) | S (26) |
| Levofloxacin | E-test | S (2) | S (2) | S (2) | S (0.5) |
| Gentamicin | Disk | S (22) | S (19) | S (20) | S (24) |
| Gentamicin | E-test | S (2) | S (4) | S (4) | S (2) |
| Gentamicin | Micro broth | S (4) | S (4) | S (4) | S (2) |
| Amikacin | Disk | S (24) | S (23) | S (22) | S (22) |
| Amikacin | Micro broth | S (8) | S (8) | S (8) | S (<4) |
| Tobramycin | Disk | S (18) | S (15) | S (15) | S (22) |
| Tobramycin | Micro broth | R (8) | R (16) | R (16) | S (2) |
| Netilmycin | Disk | S (25) | S (23) | S (22) | S (26) |
a
Results with antibiotics marked by asterisk were interpreted according to NCCLS breakpoints for Enterobacteriaceae; all others were interpreted according to NCCLS breakpoints for nonfermenting gram-negative rods; S, susceptible; I, intermediate; R, resistant.
b
Numbers in parentheses for the disk diffusion method indicate the diameters of inhibition zones (in millimeters); numbers in parentheses for the E-test and broth microdilution method indicate the MICs (in micrograms per milliliter).
c
Micro broth, broth microdilution method.
d
For trimethoprim-sulfamethoxazole, the result is expressed as the MIC of trimethoprim.