Table 5.
Selected canonical pathways altered in HF-MSS, based on Ingenuity Pathway Analysis.
| Ingenuity Canonical Pathway 1 | −log (p-Value) 2 | z-Score 3 |
|---|---|---|
| phagosome maturation | 14.6 | |
| EIF2 signaling | 14 | −2.357 |
| caveolar-mediated endocytosis signaling | 7.97 | |
| fatty acid β-oxidation I | 7.88 | 2.53 |
| TCA cycle II (Eukaryotic) | 6.89 | 2.121 |
| isoleucine degradation I | 6.83 | 2.236 |
| mitochondrial dysfunction | 6.78 | |
| valine degradation I | 4.99 | 2.236 |
| tryptophan degradation III (Eukaryotic) | 4.49 | 1.342 |
| spliceosomal cycle | 3.51 | −2.646 |
| tRNA charging | 2.43 | −1.342 |
1 Textual description of the term. 2 Negative logarithm of p-value. 3 Also called standard score, is the number of standard deviations by which the value of a raw score is above or below the mean value of what is being observed or measured.