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The human biosynthetic pathway of heme. ALAS: Aminolevulinic acid synthase, ALAD: Aminolevulinic acid dehydratase, HMBS: Hydroxymethylbilane synthase, UROS: Uroporphyrinogen III synthase, UROD: Uroporphyrinogen decarboxylase, CPOX: Coproporphyrinogen oxidase, PPOX: Protoporphyrinogen oxidase, FECH: Ferrochelatase.
