Table 1.

Blood chemistry from rats treated with Agave lechuguilla–guishe aqueous extract.

Parameter	Units	Control	DM	Control 150 mg/kg	DM 150 mg/kg	Control 300 mg/kg	DM 300 mg/kg	Control 600 mg/kg	DM 600 mg/kg
Glucose	mg/dL	131.67 ± 1.20	374.67 ± 38.68 *	118.00 ± 4.04	445.67 ± 21.54 *	116.00 ± 2.08	386.67 ± 22.82 *	134.67 ± 0.33	344.67 ± 22.45 *
Urea	mg/dL	37.70 ± 0.61	80.59 ± 3.73 *	37.43 ± 1.50	145.48 ± 1.28 *	144.51 ± 1.19	222.97 ± 13.47 *	228.91 ± 5.81	322.38 ± 8.48 *
Creatinine	mg/dL	0.27 ± 0.03	0.30 ± 0.00	1.13 ± 0.09 *	0.63 ± 0.03	1.23 ± 0.09	1.07 ± 0.17	1.27 ± 0.12	1.07 ± 0.03
Cholesterol	mg/dL	150.67 ± 0.33	152.67 ± 1.20	151.00 ± 0.58	155.67 ± 0.67	154.00 ± 2.31	154.67 ± 1.86	155.00 ± 2.65	151.67 ± 0.67
Triglycerides	mg/dL	144.33 ± 1.86	126.33 ± 1.20 *	99.67 ± 0.33	117.00 ± 2.00*	101.00 ± 2.89	85.00 ± 2.31 *	90.00 ± 3.21	86.00 ± 4.93
Uric Acid	mg/dL	1.03 ± 0.15	1.97 ± 0.13 *	3.13 ± 0.15	2.77 ± 0.32	3.30 ± 0.21	4.30 ± 0.25 *	3.70 ± 0.06	2.80 ± 0.00
T Bilirubin	mg/dL	0.10 ± 0.00	0.13 ± 0.03	0.17 ± 0.03	0.17 ± 0.03	0.23 ± 0.07	0.23 ± 0.09	0.17 ± 0.03	0.20 ± 0.06
D Bilirubin	mg/dL	0.07 ± 0.03	0.10 ± 0.00	0.03 ± 0.03	0.03 ± 0.03	0.07 ± 0.03	0.03 ± 0.03	0.03 ± 0.03	0.07 ± 0.03
ALT	U/L	106.9 ± 11.15	127.60 ± 7.39	190.60 ± 9.37	380.77 ± 11.34 *	215.20 ± 0.85	573.80 ± 20.71 *	195.40 ± 15.59	644.03 ± 4.29 *

Values express the mean ± SEM of at least n = 3 rats. ANOVA with post hoc Tukey HSD test for unbalanced data was performed. * p ≤ 0.05 controls versus DM groups. Abbreviations: T bilirubin, total bilirubin; D bilirubin, direct bilirubin; ALT, alanine aminotransferase. All determinations were carried out in blood serum obtained at the end of the 5 weeks of treatment with an aqueous extract from Agave lechuguilla–guishe. Source: authors’ own elaboration.