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. 2021 Oct 27;19(11):610. doi: 10.3390/md19110610

Scheme 2.

Scheme 2

Synthesis of compounds 137140. Reagents and conditions: (a) Oxalyl chloride, CH2Cl2, DMF, reflux, 8 h; (b) NaOH (4%), EtOH, reflux, 20 min; (c) pyridine, C4H8O2, 0 °C, 2 h.