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. 2021 Oct 27;19(11):610. doi: 10.3390/md19110610

Scheme 6.

Scheme 6

Synthesis of compound 187. Reagents and conditions: (a) Conc. HCl, FeCl3, rt, overnight; (b) malononitrile, DABCO, EtOH; (c) sodium ascorbate, CuSO4, THF/H2O.