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. 2021 Nov 25;21:446. doi: 10.1186/s12876-021-02035-6

Table 6.

Combined effect of preoperative dysbacteriosis and early postoperative diarrhoea on total postoperative complications

Variable Total patients Colon cancer Rectal cancer
Adjusted OR
(95% CI)
P for interaction Adjusted OR
(95% CI)
P for interaction Adjusted OR§
(95% CI)
P for interaction
Preoperative dysbacteriosis 0.001 0.524 0.007
Grade 1× diarrhoea 1 (reference) 1 (reference) 1 (reference)
Grade 2× diarrhea 0.98 (0.27–3.57) 0.975 0.83 (0.10–7.13) 0.866 1.05 (0.21–5.31) 0.949
Grade 3× diarrhoea 10.14 (2.93–35.05)  < 0.001 5.37 (0.28–102.46) 0.264 7.97 (2.20–28.92) 0.002

Multivariate logistic regression: Adjusted for postoperative hypoalbuminema, intraoperative blood loss, and sex. Adjusted for BMI. §Adjusted for postoperative hypoalbuminema