Between- and within-group comparisons for timing effects of EX1 and EX2 AUCs on markers of bone formation and their ratios. Between-group differences in EX AUCs were seen between 40Down trial and SED in BALP (B), CTX (C), CICP/CTX (D), and OC/CTX (E) trials; between 40 Down and 20 Up trials in OC (A), OC/CTX (E), and BALP/CTX (F); and 20 Down in OC/CTX (E). Within groups, EX1 CTX AUCs were higher than EX2 AUCs for OC (A), BALP (B), and CTX (C). EX2 AUCs were higher than EX1 AUCs for the three bone marker ratios (D–F). D = Down exercise AUC, U = Up exercise AUC, S = sedentary trial exercise AUC.