Figure 7.

Schematic illustration representing (a) multifunctional NSs with surface functionalization of PEI and HA, and DOX to treat ADR by selective targeting and stimuli-based therapy; (b) DOX release curve from functionalized NSs with or without laser irradiation; (c) statistical data of percent of cumulative DOX release for various values of pH value, enzyme, and NIR laser; (d) excised tissue photographs of multiple treatment groups (adapted with permission from Reference [52], ACS Applied Materials & Interfaces, published by American Chemical Society, 2018).