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. 2021 Nov 17;14(11):1177. doi: 10.3390/ph14111177

Table 3.

Caspase-3, Caspase-8, Bax and Bcl-2 levels for hybrid 4b and staurosporine on HepG2 cancer cell line.

Compound № Caspase-3 Caspase-8 Bax Bcl-2
Conc (pg/mL) Fold Change Conc (ng/mL) Fold Change Conc (Pg/mL) Fold Change Conc (ng/mL) Fold Change
4b 483.2 ± 14.72 5.1 1.078 ± 0.046 3.15 398.9 ± 14.3 3.75 3.659 ± 0.09 0.42
Staurosporine 445.9 ± 15.39 4.71 1.343 ± 0.026 3.93 362.2 ± 9.61 3.4 3.146 ± 0.31 0.36
Control 94.61 ± 6.5 1 0.342 ± 0.038 1 106.5 ± 5.85 1 8.623 ± 0.19 1