Table 4.
Effects of compounds 8e, 8f, 8g, and doxorubicin on active Caspases 3, 8, 9, and cytochrome C in MCF-7 breast cancer cell line.
| Compound No. | Caspase 3 | Caspase 8 | Caspase 9 | Cytochrome C | ||||
|---|---|---|---|---|---|---|---|---|
| Conc (pg/mL) |
Fold Change | Conc (ng/mL) | Fold Change | Conc (ng/mL) | Fold Change | Conc (ng/mL) | Fold Change | |
| 8e | 475.20 ± 4.27 | 7.23 | 1.29 | 7.58 | 12.89 | 13.86 | 0.548 | 11.90 |
| 8f | 365.60 ± 3.20 | 5.57 | ND | ND | ND | ND | ND | ND |
| 8g | 489.20 ± 4.13 | 7.54 | 1.52 | 8.94 | 13.98 | 15.03 | 0.587 | 12.76 |
| Doxorubicin | 503.20 ± 4.22 | 7.66 | 1.75 | 10.07 | 16.23 | 17.40 | 0.604 | 13.13 |
| Control | 65.64 | 1 | 0.17 | 1 | 0.93 | 1 | 0.046 | 1 |
ND: Not determined.